1,744 skills found · Page 1 of 59
google / LangextractA Python library for extracting structured information from unstructured text using LLMs with precise source grounding and interactive visualization.
jsvine / PdfplumberPlumb a PDF for detailed information about each char, rectangle, line, et cetera — and easily extract text and tables.
kreuzberg-dev / KreuzbergA polyglot document intelligence framework with a Rust core. Extract text, metadata, images, and structured information from PDFs, Office documents, images, and 91+ formats. Available for Rust, Python, Ruby, Java, Go, PHP, Elixir, C#, R, C, TypeScript (Node/Bun/Wasm/Deno)- or use via CLI, REST API, or MCP server.
allure-framework / Allure2Allure Report is a flexible, lightweight multi-language test reporting tool. It provides clear graphical reports and allows everyone involved in the development process to extract the maximum of information from the everyday testing process
grobidOrg / GrobidA machine learning software for extracting information from scholarly documents
megadose / ToutatisToutatis is a tool that allows you to extract information from instagrams accounts such as e-mails, phone numbers and more
reactjs / React DocgenA CLI and library to extract information from React component files for documentation generation purposes.
NAalytics / Assemblies Of Putative SARS CoV2 Spike Encoding MRNA Sequences For Vaccines BNT 162b2 And MRNA 1273RNA vaccines have become a key tool in moving forward through the challenges raised both in the current pandemic and in numerous other public health and medical challenges. With the rollout of vaccines for COVID-19, these synthetic mRNAs have become broadly distributed RNA species in numerous human populations. Despite their ubiquity, sequences are not always available for such RNAs. Standard methods facilitate such sequencing. In this note, we provide experimental sequence information for the RNA components of the initial Moderna (https://pubmed.ncbi.nlm.nih.gov/32756549/) and Pfizer/BioNTech (https://pubmed.ncbi.nlm.nih.gov/33301246/) COVID-19 vaccines, allowing a working assembly of the former and a confirmation of previously reported sequence information for the latter RNA. Sharing of sequence information for broadly used therapeutics has the benefit of allowing any researchers or clinicians using sequencing approaches to rapidly identify such sequences as therapeutic-derived rather than host or infectious in origin. For this work, RNAs were obtained as discards from the small portions of vaccine doses that remained in vials after immunization; such portions would have been required to be otherwise discarded and were analyzed under FDA authorization for research use. To obtain the small amounts of RNA needed for characterization, vaccine remnants were phenol-chloroform extracted using TRIzol Reagent (Invitrogen), with intactness assessed by Agilent 2100 Bioanalyzer before and after extraction. Although our analysis mainly focused on RNAs obtained as soon as possible following discard, we also analyzed samples which had been refrigerated (~4 ℃) for up to 42 days with and without the addition of EDTA. Interestingly a substantial fraction of the RNA remained intact in these preparations. We note that the formulation of the vaccines includes numerous key chemical components which are quite possibly unstable under these conditions-- so these data certainly do not suggest that the vaccine as a biological agent is stable. But it is of interest that chemical stability of RNA itself is not sufficient to preclude eventual development of vaccines with a much less involved cold-chain storage and transportation. For further analysis, the initial RNAs were fragmented by heating to 94℃, primed with a random hexamer-tailed adaptor, amplified through a template-switch protocol (Takara SMARTerer Stranded RNA-seq kit), and sequenced using a MiSeq instrument (Illumina) with paired end 78-per end sequencing. As a reference material in specific assays, we included RNA of known concentration and sequence (from bacteriophage MS2). From these data, we obtained partial information on strandedness and a set of segments that could be used for assembly. This was particularly useful for the Moderna vaccine, for which the original vaccine RNA sequence was not available at the time our study was carried out. Contigs encoding full-length spikes were assembled from the Moderna and Pfizer datasets. The Pfizer/BioNTech data [Figure 1] verified the reported sequence for that vaccine (https://berthub.eu/articles/posts/reverse-engineering-source-code-of-the-biontech-pfizer-vaccine/), while the Moderna sequence [Figure 2] could not be checked against a published reference. RNA preparations lacking dsRNA are desirable in generating vaccine formulations as these will minimize an otherwise dramatic biological (and nonspecific) response that vertebrates have to double stranded character in RNA (https://www.nature.com/articles/nrd.2017.243). In the sequence data that we analyzed, we found that the vast majority of reads were from the expected sense strand. In addition, the minority of antisense reads appeared different from sense reads in lacking the characteristic extensions expected from the template switching protocol. Examining only the reads with an evident template switch (as an indicator for strand-of-origin), we observed that both vaccines overwhelmingly yielded sense reads (>99.99%). Independent sequencing assays and other experimental measurements are ongoing and will be needed to determine whether this template-switched sense read fraction in the SmarterSeq protocol indeed represents the actual dsRNA content in the original material. This work provides an initial assessment of two RNAs that are now a part of the human ecosystem and that are likely to appear in numerous other high throughput RNA-seq studies in which a fraction of the individuals may have previously been vaccinated. ProtoAcknowledgements: Thanks to our colleagues for help and suggestions (Nimit Jain, Emily Greenwald, Lamia Wahba, William Wang, Amisha Kumar, Sameer Sundrani, David Lipman, Bijoyita Roy). Figure 1: Spike-encoding contig assembled from BioNTech/Pfizer BNT-162b2 vaccine. Although the full coding region is included, the nature of the methodology used for sequencing and assembly is such that the assembled contig could lack some sequence from the ends of the RNA. Within the assembled sequence, this hypothetical sequence shows a perfect match to the corresponding sequence from documents available online derived from manufacturer communications with the World Health Organization [as reported by https://berthub.eu/articles/posts/reverse-engineering-source-code-of-the-biontech-pfizer-vaccine/]. The 5’ end for the assembly matches the start site noted in these documents, while the read-based assembly lacks an interrupted polyA tail (A30(GCATATGACT)A70) that is expected to be present in the mRNA.
naiveHobo / InvoiceNetDeep neural network to extract intelligent information from invoice documents.
fhamborg / News Pleasenews-please - an integrated web crawler and information extractor for news that just works
crownpku / Information Extraction ChineseChinese Named Entity Recognition with IDCNN/biLSTM+CRF, and Relation Extraction with biGRU+2ATT 中文实体识别与关系提取
symfony / Property InfoExtracts information about PHP class' properties using metadata of popular sources
xaitax / TotalRecallThis tool extracts and displays data from the Recall feature in Windows 11, providing an easy way to access information about your PC's activity snapshots.
allmarkedup / Purl[NO LONGER MAINTAINED] A JS utility for for parsing URLs and extracting information out of them.
impira / DocqueryAn easy way to extract information from documents
Jon-Becker / Heimdall RsHeimdall is an advanced EVM smart contract toolkit specializing in bytecode analysis and extracting information from unverified contracts.
Arvanaghi / SessionGopherSessionGopher is a PowerShell tool that uses WMI to extract saved session information for remote access tools such as WinSCP, PuTTY, SuperPuTTY, FileZilla, and Microsoft Remote Desktop. It can be run remotely or locally.
Borewit / Music MetadataMetadata parser for audio and video media files. Supports file and stream inputs in Node.js and browser environments, extracting format, tag, and duration information.
SciresM / Hactoolhactool is a tool to view information about, decrypt, and extract common file formats for the Nintendo Switch, especially Nintendo Content Archives.
OmkarPathak / PyresparserA simple resume parser used for extracting information from resumes
