402 skills found · Page 11 of 14
jaechang-hits / science-figure-guideScience (AAAS) figure preparation: resolution (150-300+ DPI), formats (PDF/EPS/TIFF), RGB color, Myriad/Helvetica fonts, strict image manipulation policies including gamma adjustment disclosure.
jaechang-hits / medchemMedicinal chemistry filters for compound triage. Drug-likeness rules (Lipinski Ro5, Veber, Oprea, CNS, leadlike, REOS, Golden Triangle, Ro3), structural alerts (PAINS, NIBR, Lilly Demerits), chemical group detectors, complexity metrics, and filter composition query language. Built on RDKit/datamol.
jaechang-hits / rdkit-cheminformaticsCheminformatics toolkit for molecular analysis and virtual screening: SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints (Morgan/ECFP, MACCS), Tanimoto similarity, SMARTS substructure filtering, Lipinski drug-likeness, reaction enumeration, 2D/3D coordinates.
jaechang-hits / rowanCloud quantum chemistry platform with Python SDK. Run geometry optimization, conformer generation, torsional scans, and energy minimization (DFT/semiempirical), and retrieve properties (dipole, partial charges, frontier orbitals) — no local QC software or HPC needed.
jaechang-hits / cellchat-cell-communicationInfer and visualize intercellular communication from scRNA-seq with CellChat (R). Build CellChat from Seurat/counts → subset CellChatDB ligand-receptor pairs → over-expressed genes per group → communication probabilities → pathway signaling → network centrality (senders/receivers/influencers) → chor…
jaechang-hits / cobrapy-metabolic-modelingConstraint-based (COBRA) analysis of genome-scale metabolic models: FBA, FVA, knockouts, flux sampling, production envelopes, gapfilling, media optimization. Use for strain design, essential gene ID, flux analysis. For kinetic modeling use tellurium; for visualization use Escher.
jaechang-hits / samtools-bam-processingCLI toolkit for SAM/BAM/CRAM: sort, index, convert, filter, QC alignments. Core commands: view, sort, index, flagstat, stats, depth, markdup, merge. Required between alignment and variant/peak calling. Use pysam for Python-native BAM access; deeptools for normalized coverage tracks.
jaechang-hits / gtarsRust-backed Python library for fast genomic token arithmetic and BED processing. High-performance BED I/O, interval set ops (intersect, merge, complement, subtract), region tokenization against a universe, universe construction. Use for preprocessing large BED collections and ML token vocabularies.
jaechang-hits / deseq2-differential-expressionBulk RNA-seq DE with R/Bioconductor DESeq2. Negative binomial GLM, empirical Bayes shrinkage, Wald/LRT tests, multi-factor designs, Salmon tximeta import, apeglm LFC shrinkage, MA/volcano/heatmap viz. R gold standard. Use pydeseq2-differential-expression for Python; use edgeR for TMM normalization.
jaechang-hits / lancet-figure-guideThe Lancet figure preparation: resolution (300+ DPI at 120%), preferred editable formats (PowerPoint/Word/SVG), column widths (75/154 mm), Times New Roman, in-house redraw policy.
datadrivenconstruction / enterprise-risk-aggregatorAggregate and analyze risks across construction project portfolio. Identify correlated risks, systemic exposures, and portfolio-level risk mitigation strategies.
datadrivenconstruction / ifc-data-extractionExtract structured data from IFC (Industry Foundation Classes) files using IfcOpenShell. Parse BIM models, extract quantities, properties, spatial relationships, and export to various formats.
datadrivenconstruction / resource-pool-optimizerOptimize shared resource pools across multiple construction projects. Balance resource allocation, minimize conflicts, and maximize utilization across the portfolio.
datadrivenconstruction / productivity-analyzerAnalyze labor productivity from site data. Compare planned vs actual, identify trends, benchmark against industry standards.
datadrivenconstruction / project-kpi-dashboardCreate interactive KPI dashboards for construction projects. Track schedule, cost, quality, and safety metrics in real-time.
datadrivenconstruction / bim-clash-detectionDetect and analyze geometric clashes in BIM models. Identify MEP, structural, and architectural conflicts before construction.
datadrivenconstruction / bim-classification-aiClassify BIM elements using AI and standard classification systems. Map elements to UniFormat, MasterFormat, OmniClass, and CWICR codes.
datadrivenconstruction / co2-carbon-footprintCalculate CO2 emissions and carbon footprint from BIM model data. Analyze embodied carbon by material, element, and building system.
datadrivenconstruction / ifc-qto-extractionExtract quantities from IFC/Revit models for quantity takeoff. Uses DDC converters to get element counts, areas, volumes, lengths with grouping and reporting.
datadrivenconstruction / progress-photo-analyzerAnalyze construction site photos to track progress, detect safety issues, and compare against BIM models using computer vision.
datadrivenconstruction / batch-cad-converterBatch convert multiple CAD/BIM files (Revit, IFC, DWG, DGN) with progress tracking, error handling, and consolidated reporting.
datadrivenconstruction / cwicr-assembly-builderBuild cost assemblies from CWICR work items. Combine multiple items into reusable templates for common construction elements.
datadrivenconstruction / cwicr-comparison-toolCompare cost estimates across projects, versions, and scenarios. Identify variances, benchmark against standards, and generate comparison reports.
datadrivenconstruction / cwicr-cost-calculatorCalculate construction costs using DDC CWICR resource-based methodology. Break down costs into labor, materials, equipment with transparent pricing.
datadrivenconstruction / cwicr-crew-optimizerOptimize crew composition using CWICR labor norms. Balance productivity, cost, and skill requirements for construction crews.
datadrivenconstruction / cwicr-equipment-plannerPlan equipment requirements using CWICR norms. Calculate equipment hours, scheduling, utilization rates, and rental vs purchase analysis.
datadrivenconstruction / cwicr-escalationApply price escalation to CWICR estimates over time. Calculate inflation adjustments, material price indices, and labor rate increases.
datadrivenconstruction / cwicr-location-factorApply geographic location factors to CWICR estimates. Adjust costs for regional labor rates, material prices, and market conditions.
datadrivenconstruction / cwicr-material-procurementGenerate material procurement lists from CWICR data. Calculate quantities with waste factors, group by supplier categories, and create purchase orders.
datadrivenconstruction / cwicr-productivity-trackerTrack actual vs planned productivity using CWICR norms. Calculate productivity rates, identify variances, and generate performance reports.
