513 skills found · Page 16 of 18
jaechang-hits / ensembl-databaseEnsembl REST API for gene/transcript/variant annotations in 300+ species. Gene info by symbol/ID, sequence, cross-refs (HGNC, RefSeq, UniProt), regulatory features. For bulk local use pyensembl; for pathways use kegg-database.
jaechang-hits / gene-databaseNCBI Gene via E-utilities: curated records across 1M+ taxa. Official symbols, aliases, RefSeq IDs, summaries, coordinates, GO, interactions. Use for gene ID resolution and cross-species function queries. For sequences use Ensembl; for expression use geo-database.
jaechang-hits / geo-databaseNCBI GEO access via GEOparse and E-utilities. Search by keyword/organism/platform, download GSE series matrices, parse GPL annotations, extract GSM metadata, load expression matrices into pandas. For single-cell use cellxgene-census; for multi-DB access use gget-genomic-databases.
jaechang-hits / gget-genomic-databasesUnified CLI/Python interface to 20+ genomic databases. Gene lookups (Ensembl search/info/seq), BLAST/BLAT, AlphaFold, Enrichr enrichment, OpenTargets disease/drug, CELLxGENE single-cell, cBioPortal/COSMIC cancer, ARCHS4 expression. Spans genomics, proteomics, disease.
jaechang-hits / gnomad-databasegnomAD v4 population variant frequencies via GraphQL API. Allele counts and frequencies stratified by ancestry (AFR, AMR, EAS, NFE, SAS, FIN, ASJ, MID), gene-level constraint (pLI, LOEUF, missense z), and coverage. Identify rare or constrained variants.
jaechang-hits / gwas-databaseNHGRI-EBI GWAS Catalog REST API for SNP-trait associations from published GWAS. Query studies, associations, variants, traits, genes, summary stats. Build PRS candidates, analyze pleiotropy, fetch stats for Manhattan plots. No auth.
jaechang-hits / jaspar-databaseJASPAR 2024 TF binding profiles via REST API and pyJASPAR. Retrieve PFMs/PWMs by TF name, JASPAR ID, species, or structural class. Scan DNA for TFBS; browse by taxon (human, mouse) or TF family (bHLH, zinc finger). Use for motif enrichment input, TFBS scanning, and regulatory sequence analysis.
jaechang-hits / kegg-databaseKEGG REST API (academic only). Pathways, genes, compounds, enzymes, diseases, drugs via 7 ops (info/list/find/get/conv/link/ddi). ID conversion (NCBI/UniProt/PubChem). Use bioservices for multi-DB Python.
jaechang-hits / monarch-databaseMonarch Initiative knowledge graph REST API for disease-gene-phenotype associations and cross-species orthology. MONDO disease-to-gene/phenotype, HP phenotype profiles, cross-species comparisons. Use for rare disease gene prioritization and phenotype-based candidate ranking.
jaechang-hits / mouse-phenome-databaseRetrieve mouse phenotype data from the Jackson Laboratory Mouse Phenome Database (MPD) via its REST API. Browse 520+ projects, look up per-project measure metadata, pull strain-level means (raw or LS-mean adjusted) and per-animal values, find measures by MP/VT ontology terms, and resolve strain nome…
jaechang-hits / quickgo-databaseQuery EBI QuickGO REST API for GO terms and protein annotations. Fetch term metadata by ID, search by keyword, walk ancestor/descendant hierarchies, download annotations filtered by taxon, evidence code, aspect. Use for GO resolution, ontology traversal, annotation retrieval before enrichment.
jaechang-hits / regulomedb-databaseQuery RegulomeDB v2 GET REST API to score variants for regulatory function and retrieve overlapping evidence (TF binding, histone marks, DNase peaks, footprints, motifs, eQTLs, chromatin state). Scores range 1a (strongest) to 7 (none).
jaechang-hits / remap-databaseQuery ReMap 2022 TF ChIP-seq peak database via REST API and BED downloads. Retrieve TF peaks overlapping a region (chr:start-end), peaks near a gene, TFs by species, peaks filtered by biotype (promoter, enhancer), and BED files for a TF-cell type pair.
jaechang-hits / deeptools-ngs-analysisNGS CLI for ChIP/RNA/ATAC-seq. BAM→bigWig with RPGC/CPM/RPKM, sample correlation/PCA, heatmaps/profiles around features, fingerprints. For alignment use STAR/BWA; for peak calling use MACS2.
jaechang-hits / gseapy-gene-enrichmentGSEA and over-representation analysis (ORA) for RNA-seq and proteomics. Wraps Enrichr for ORA against MSigDB, KEGG, GO, and 200+ databases; runs preranked GSEA on ranked DE gene lists. Outputs enrichment tables and running-score plots. Use after DESeq2 or edgeR for pathway-level interpretation.
jaechang-hits / literature-reviewConducting systematic, scoping, and narrative literature reviews. Covers PRISMA/PRISMA-ScR protocols, search strategy (Boolean, MeSH), database selection (PubMed, Scopus, Web of Science, Embase), screening, data extraction, evidence synthesis (narrative, meta-analysis, thematic), and reporting
giuseppe-trisciuoglio / chunking-strategyProvides chunking strategies for RAG systems. Generates chunk size recommendations (256-1024 tokens), overlap percentages (10-20%), and semantic boundary detection methods. Validates semantic coherence and evaluates retrieval precision/recall metrics
giuseppe-trisciuoglio / aws-rds-spring-boot-integrationProvides patterns to configure AWS RDS (Aurora, MySQL, PostgreSQL) with Spring Boot applications. Configures HikariCP connection pools, implements read/write splitting, sets up IAM database authentication, enables SSL connections, and integrates with AWS Secrets Manager
giuseppe-trisciuoglio / unit-test-parameterizedProvides parameterized testing patterns with JUnit 5, generates data-driven unit tests using @ParameterizedTest, @ValueSource, @CsvSource, @MethodSource. Creates tests that run the same logic with multiple input values
giuseppe-trisciuoglio / nestjs-code-reviewProvides comprehensive code review capability for NestJS applications, analyzing controllers, services, modules, guards, interceptors, pipes, dependency injection, and database integration patterns
giuseppe-trisciuoglio / spring-data-neo4jProvides Spring Data Neo4j integration patterns for Spring Boot applications
giuseppe-trisciuoglio / nestjsProvides comprehensive NestJS framework patterns with Drizzle ORM integration for building scalable server-side applications. Generates REST/GraphQL APIs, implements authentication guards, creates database schemas, and sets up microservices
giuseppe-trisciuoglio / spring-data-jpaProvides patterns to implement persistence layers with Spring Data JPA
giuseppe-trisciuoglio / unit-test-service-layerProvides patterns for unit testing service layer with Mockito. Creates isolated tests that mock repository calls, verify method invocations, test exception scenarios, and stub external API responses
giuseppe-trisciuoglio / drizzle-orm-patternsProvides comprehensive Drizzle ORM patterns for schema definition, CRUD operations, relations, queries, transactions, and migrations.
giuseppe-trisciuoglio / nestjs-drizzle-crud-generatorGenerates complete CRUD modules for NestJS applications with Drizzle ORM
AlpacaLabsLLC / product-researchFind and compare current FF&E candidates from a design brief, with sourced purchasing facts and optional CSV-library save. Use to research or source products; not to match from an image or pair coordinating items.
kazukinagata / journalThis skill should be used when the user wants to record bookkeeping entries (仕訳), import transaction data from CSV files, receipts, or invoices, or manage their general ledger.
datadrivenconstruction / labor-productivity-analyticsAnalyze construction labor productivity using data analytics. Track worker performance, identify inefficiencies, predict resource needs, and optimize crew allocation for maximum efficiency.
datadrivenconstruction / portfolio-dashboardMulti-project portfolio analytics dashboard. Aggregate KPIs across projects, track portfolio health, compare performance, and support executive decision-making.
