📣 Announcement (07/01/2025) 📣

IGoR's development has been on stale for the past few years. At last a new development sprint will be carried this year to rehaul IGoR's install, improve python bindings, improve maintenability, fix bugs and introduce new features and models.

As a first step, this legacy 1.4 version can now be installed via conda using the following command:

conda install -c nniclausse -c conda-forge igor

IGoR: Inference and Generation Of Repertoires

This repository contains all sources and models useful to infer V(D)J recombination related processes for TCR or BCR sequencing data using IGoR.

IGoR's exhaustive documentation can be found http://qmarcou.github.io/IGoR[here]!

Download the latest release https://github.com/qmarcou/IGoR/releases[here].

[[quick-summary]] Quick summary

IGoR is a C++ software designed to infer V(D)J recombination related processes from sequencing data such as:

• Recombination model probability distribution
• Hypermutation model
• Best candidates recombination scenarios
• Generation probabilities of sequences (even hypermutated)

The following paper describes the methodology, performance tests and some new biological results obtained with IGoR:

https://www.nature.com/articles/s41467-018-02832-w[High-throughput immune repertoire analysis with IGoR], Nature Communications, (2018) Quentin Marcou, Thierry Mora, Aleksandra M. Walczak

Its heavily object oriented and modular style was designed to ensure long term support and evolvability for new tasks in assessing TCR and BCR receptors features using modern parallel architectures.

IGoR is a free (as in freedom) software released under the https://www.gnu.org/licenses/quick-guide-gplv3.html[GNU-GPLv3] license.

[[version]] Version

include::./docs/asciidoc/version.adoc[] Download the latest release https://github.com/qmarcou/IGoR/releases[here].

Documentation

A comprehensive documentation of IGoR is available on the internet at: http://qmarcou.github.io/IGoR[http://qmarcou.github.io/IGoR] or in your local installation of IGoR as the ./docs/index.html file.

include::./docs/asciidoc/general/contribute.adoc[]

[[contact]] Contact

For any question or issue please open an https://github.com/qmarcou/IGoR/issues[issue] or email mailto:quentin.marcou@lpt.ens.fr[us].

Copying

Free use of IGoR is granted under the terms of the https://www.gnu.org/licenses/quick-guide-gplv3.html[GNU General Public License version 3] (GPLv3).