SPiCCAto
Software developed to study the influence of the extracellular matrix in cell migration.
Install / Use
/learn @phydev/SPiCCAtoREADME
Software PaCkage for Cell reseArch
This project is hosted by the CFisUC at the University of Coimbra and consists in a phase-field model for multicellular systems.
This software was developed to study how the mechanical constraints imposed by the extracellular matrix (ECM) affect cell migration. We explored a phase-field model that describes the fibres and the cell as order parameters that interact by repulsion and adhesion.
Publications
M. Moreira-Soares, S. Pinto-Cunha, J. R. Bordin, R. D. M. Travasso. "Adhesion modulates cell morphology and migration within dense fibrous networks". https://doi.org/10.1101/838995
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