alphagenome-variant-impact-score
Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular callsets, perform saturation mutagenesis window scans (1-based closed chr:start-end), and extract GENCODE v46 GTF gene/…
Install / Use
npx skills add google-deepmind/science-skills --skill alphagenome_variant_impact_scoreInstalls into whichever agent you are using.
SKILL.md
Installable skill definition
Quality Score
Category
Development & EngineeringSupported Platforms
Our assessment of alphagenome-variant-impact-score
alphagenome-variant-impact-score scores 86/100 on our quality scale, 1267th of 3,045 Development & Engineering skills we index (top 42%).
We have not analysed the SKILL.md file itself yet, so the content part of this score is an estimate until our crawler reaches it.
With 3,137 GitHub stars, it is one of the more widely adopted skills in the catalogue.
Maintenance, license and trust
- The repository was last updated 12 days ago, so alphagenome-variant-impact-score is actively maintained.
- It is released under the Apache-2.0 license, a permissive license that allows use, modification and commercial use with attribution.
- Its trust signals score 100/100, with no cautions. These come from repository metadata, not a code audit — read the skill file before letting an agent act on it.
alphagenome-variant-impact-score compared with similar skills
All 4 of these similar skills score higher than alphagenome-variant-impact-score; compare them before choosing.
| Skill | Score | Stars | Updated | Format |
|---|---|---|---|---|
| alphagenome-variant-impact-score (this skill)by google-deepmind | 86 | 3.1k | 12d ago | SKILL.md |
| Agent-Reachby Panniantong | 100 | 85.9k | 12d ago | CLAUDE.md |
| headroomby headroomlabs-ai | 100 | 74.0k | 1d ago | CLAUDE.md |
| ai-job-searchby MadsLorentzen | 100 | 44.3k | today | CLAUDE.md |
| claude-howtoby luongnv89 | 100 | 41.7k | 2d ago | CLAUDE.md |
Frequently asked questions
- How do I install alphagenome-variant-impact-score?
- Run
npx skills add google-deepmind/science-skills --skill alphagenome-variant-impact-score. The install tabs above show the steps for each supported agent. - Which AI agents does alphagenome-variant-impact-score work with?
- It is written for Universal, as a SKILL.md file. Other agents that read the same format can often use it too.
- Is alphagenome-variant-impact-score safe to use?
- It is Apache-2.0-licensed and scores 100/100 on trust signals. Skills are instructions an agent will follow, so read the file before installing it and do not approve commands you do not understand.
- Is alphagenome-variant-impact-score still maintained?
- The repository was last updated 12 days ago, so alphagenome-variant-impact-score is actively maintained.
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Languages
Trust signals
From repository metadata: license, adoption, age and documentation. Not a code audit — see the Safety scan above for what the skill file itself contains.