NPARC

Nonparametric Analysis of Response Curves from Thermal Proteome Profiling Experiments.
R package implementation of the method described by Childs, Bach, Franken et al. (2019) Mol. Cell. Proteomics.

Installation

Installation from Bioconductor (recommended)

NPARC is in the process of being made available through Bioconductor! Therefore, the most reliable way to install it is via BiocManager:

if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("NPARC")

Installation of the development version

if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install(“Huber-group-EMBL/NPARC”)

Getting started

The easiest way of learning how to use the NPARC package is to browse it's vignette:

library(NPARC)
browseVignettes("NPARC")