1,801 skills found · Page 24 of 61
microsoft / azure-enterprise-infra-plannerArchitect and provision enterprise Azure infrastructure from workload descriptions. For cloud architects and platform engineers planning networking, identity, security, compliance, and multi-resource topologies with WAF alignment. Generates Bicep or Terraform directly (no azd).
microsoft / frontend-design-reviewReview and create distinctive, production-grade frontend interfaces with high design quality and design system compliance. Evaluates using three pillars: frictionless insight-to-action, quality craft, and trustworthy building.
microsoft / azure-kubernetesPlan, create, and configure production-ready Azure Kubernetes Service (AKS) clusters. Covers Day-0 checklist, SKU selection (Automatic vs Standard), networking options (private API server, Azure CNI Overlay, egress configuration), security, and operations (autoscaling, upgrade strategy, cost analysi…
FreedomIntelligence / bio-crispr-screens-library-designCRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering
FreedomIntelligence / adhd-daily-plannerTime-blind friendly planning, executive function support, and daily structure for ADHD brains. Specializes in realistic time estimation, dopamine-aware task design, and building systems that
FreedomIntelligence / bio-genome-engineering-base-editing-designDesign guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Select optimal positions for C-to-T or A-to-G conversions without double-strand breaks
FreedomIntelligence / bio-genome-engineering-grna-designDesign guide RNAs for CRISPR-Cas9/Cas12a experiments using CRISPRscan and local scoring algorithms. Score guides for on-target activity using Rule Set 2 and Azimuth models
FreedomIntelligence / bio-genome-engineering-hdr-template-designDesign homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms
FreedomIntelligence / bio-genome-engineering-prime-editing-designDesign pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks
FreedomIntelligence / bio-immunoinformatics-epitope-predictionPredict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens
FreedomIntelligence / bio-immunoinformatics-immunogenicity-scoringScore and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design
FreedomIntelligence / bio-immunoinformatics-mhc-binding-predictionPredict peptide-MHC class I and II binding affinity using MHCflurry and NetMHCpan neural network models. Identify potential T-cell epitopes from protein sequences
FreedomIntelligence / alphafoldValidate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain c…
FreedomIntelligence / bindcraftEnd-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5)…
FreedomIntelligence / binder-designGuidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types.
FreedomIntelligence / armored-cart-design-agentThe Armored CAR-T Design Agent provides AI-assisted design of next-generation armored CAR-T cells engineered to express cytokines, chemokines, or other enhancing factors.
FreedomIntelligence / aav-vector-design-agentThe AAV Vector Design Agent provides AI-driven design of adeno-associated virus vectors for gene therapy applications. It covers capsid selection and engineering, promoter/enhancer design, transgene optimization, and manufacturing considerations.
FreedomIntelligence / bio-experimental-design-power-analysisPower = probability of detecting a true effect. Underpowered studies waste resources; overpowered studies are inefficient.
FreedomIntelligence / bio-experimental-design-sample-sizeWhen resources are limited, prioritize: 1. Biological replicates over technical replicates 2. More samples over deeper sequencing (after ~20M reads for RNA-seq) 3. Balanced designs (equal n per group)
FreedomIntelligence / bio-experimental-design-multiple-testingTesting 20,000 genes at p < 0.05 yields ~1,000 false positives by chance. Correction is essential.
FreedomIntelligence / bio-experimental-design-batch-designBatch effects are unavoidable. Good design makes them correctable.
silexlabs / SilexSilex is an online tool for visually creating static sites with dynamic data. With the free/libre spirit of internet, together.
cloudflare / cloudflare-oneDesign, configure, troubleshoot, or review Cloudflare One Zero Trust and SASE deployments. Use cloudflare-one-migrations for migration planning from other vendors.
tradermonty / edge-pipeline-orchestratorOrchestrate the full edge research pipeline from candidate detection through strategy design, review, revision, and export
tradermonty / edge-hint-extractorExtract edge hints from daily market observations and news reactions, with optional LLM ideation, and output canonical hints.yaml for downstream concept synthesis and auto detection.
tradermonty / edge-strategy-reviewerCritically review strategy drafts from edge-strategy-designer for edge plausibility, overfitting risk, sample size adequacy, and execution realism
tradermonty / strategy-pivot-designerDetect backtest iteration stagnation and generate structurally different strategy pivot proposals when parameter tuning reaches a local optimum.
tradermonty / skill-designerDesign new Claude skills from structured idea specifications
tradermonty / trade-hypothesis-ideatorGenerate falsifiable trade strategy hypotheses from market data, trade logs, and journal snippets
tradermonty / edge-strategy-designerConvert abstract edge concepts into strategy draft variants and optional exportable ticket YAMLs for edge-candidate-agent export/validation.