170 skills found · Page 2 of 6
JonnyTran / OpenOmicsA bioinformatics API to interface with public multi-omics bio databases for wicked fast data integration.
AstraZeneca / StarGazerStarGazer is a tool designed for rapidly assessing drug repositioning opportunities. It combines multi-source, multi-omics data with a novel target prioritization scoring system in an interactive Python-based Streamlit dashboard. StarGazer displays target prioritization scores for genes associated with 1844 phenotypic traits.
wuyangf7 / OPERAThis software tool implements the OPERA (omics pleiotropic association) method to test for combinatorial pleiotropic associations of molecular phenotypes (e.g., expression level of a gene and DNA methylation level at CpG sites) with a complex trait of interest using summary-level data from GWAS and molecular QTL studies. OPERA is a Bayesian generalization of the SMR & HEIDI approach8 to a multi-omics model, where the molecular phenotypes are considered as exposures and only the complex trait is considered as the outcome. This tool can therefore be used to prioritize molecular phenotypes that mediate the genetic effects for complex trait and provide mechanistic interpretation of the GWAS signal.
seasoncloud / AlleloscopeAlleloscope is a method for allele-specific copy number estimation that can be applied to single cell DNA and ATAC sequencing data (separately or in combination). Allele-specific estimation allows for the more accurate delineation of copy number states and the detection of subclonal copy-neutral loss-of-heterozygosity and mirrored CNA events. On scATAC-seq data, Alleloscope allows integrative multi-omic analysis of allele-specific copy number and chromatin accessibility for the same cell.
cantinilab / HuMMuSMolecular interactions inference from single-cell multi-omics data
sqjin / ScAIAn unsupervised approach for the integrative analysis of single-cell multi-omics data
jan-forest / AutoencodixFramework for multi-omics data integration by autoencoders
bioFAM / ScDoRIscDoRI (single-cell Deep multi-Omic Regulatory Inference) is a deep learning model to infer enhancer-mediated gene regulatory networks (eGRNs) from single-cell multiome data (RNA + ATAC).
himelmallick / TweedieverseDifferential analysis of multi-omics data based on the Tweedie distribution
krassowski / Multi Omics State Of The FieldAnalyses for "State of the field in multi-omics research: from computational needs to data mining and sharing"
AstraZeneca / OmicsfoldMulti-omics data normalisation, model fitting and visualisation.
mkanai / GrimonR package for plotting 3D graphical visualization of multi-omics data.
abodein / TimeOmicsTime-Course Multi-Omics data integration
glasgowcompbio / PyMultiOmicsPython toolbox for multi-omics data mapping and analysis
SeedLLM / Mollymolly, an LLM designed to understand multi-omics data.
chl8856 / DeepIMVA Variational Information Bottleneck Approach to Multi-Omics Data Integration
awslabs / Guidance For Multi Omics And Multi Modal Data Integration And Analysis On AwsThis guidance creates a scalable environment in AWS to prepare genomic, clinical, mutation, expression and imaging data for large-scale analysis and perform interactive queries against a data lake. The solution also demonstrates the use of Amazon Omics for multi-modal analysis.
waldronlab / MultiAssayWorkshopMulti-omic Integration and Analysis of cBioPortal and TCGA data with MultiAssayExperiment
OSU-BMBL / MarsgtMulti-omics data analysis for rare population inference using single-cell graph transformer
gefeiwang / ScMODALscMODAL: A general deep learning framework for single-cell Multi-Omics Data Alignment with feature Links
