440 skills found · Page 6 of 15
google-deepmind / alphafold-database-fetch-and-analyzeRetrieve and analyze AlphaFold predicted structures for a protein
google-deepmind / gnomad-databaseQuery the Genome Aggregation Database (gnomAD)
google-deepmind / string-databaseQuery the STRING database for protein-protein interactions (PPIs), functional enrichment, and homology
google-deepmind / foldseek-structural-searchPerforms 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate file (.cif, .mmcif, or .pdb) and wants to find structurally similar proteins.
google-deepmind / protein-sequence-msaPerforms multiple sequence alignment of proteins with EBI Clustal Omega
microsoft / azure-resource-manager-mysql-dotnetAzure MySQL Flexible Server SDK for .NET. Database management for MySQL Flexible Server deployments. Use for creating servers, databases, firewall rules, configurations, backups, and high availability.
microsoft / azure-resource-manager-postgresql-dotnetAzure PostgreSQL Flexible Server SDK for .NET. Database management for PostgreSQL Flexible Server deployments. Use for creating servers, databases, firewall rules, configurations, backups, and high availability.
microsoft / azure-postgres-tsConnect to Azure Database for PostgreSQL Flexible Server from Node.js/TypeScript using the pg (node-postgres) package. Use for PostgreSQL queries, connection pooling, transactions, and Microsoft Entra ID (passwordless) authentication.
microsoft / azure-resource-manager-cosmosdb-dotnetAzure Resource Manager SDK for Cosmos DB in .NET. Use for MANAGEMENT PLANE operations: creating/managing Cosmos DB accounts, databases, containers, throughput settings, and RBAC via Azure Resource Manager
microsoft / azure-resource-manager-sql-dotnetAzure Resource Manager SDK for Azure SQL in .NET. Use for MANAGEMENT PLANE operations: creating/managing SQL servers, databases, elastic pools, firewall rules, and failover groups via Azure Resource Manager
microsoft / azure-cosmos-javaAzure Cosmos DB SDK for Java. NoSQL database operations with global distribution, multi-model support, and reactive patterns. Triggers: "CosmosClient java", "CosmosAsyncClient", "cosmos database java", "cosmosdb java", "document database java".
microsoft / azure-cosmos-pyAzure Cosmos DB SDK for Python (NoSQL API). Use for document CRUD, queries, containers, and globally distributed data. Triggers: "cosmos db", "CosmosClient", "container", "document", "NoSQL", "partition key".
microsoft / azure-kustoQuery and analyze data in Azure Data Explorer (Kusto/ADX) using KQL for log analytics, telemetry, and time series analysis. WHEN: KQL queries, Kusto database queries, Azure Data Explorer, ADX clusters, log analytics, time series data, IoT telemetry, anomaly detection.
microsoft / azure-mgmt-mongodbatlas-dotnetManage MongoDB Atlas Organizations as Azure ARM resources using Azure.ResourceManager.MongoDBAtlas SDK
microsoft / azure-cosmos-db-pyBuild Azure Cosmos DB NoSQL services with Python/FastAPI following production-grade patterns
microsoft / frontend-design-reviewReview and create distinctive, production-grade frontend interfaces with high design quality and design system compliance. Evaluates using three pillars: frictionless insight-to-action, quality craft, and trustworthy building.
FreedomIntelligence / alphafold-databaseAccess AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
FreedomIntelligence / bindingdb-databaseQuery BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
FreedomIntelligence / bio-clinical-databases-somatic-signaturesExtract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns to characterize mutagenic processes
FreedomIntelligence / arxiv-searchSearch arXiv physics, math, and computer science preprints using natural language queries. Powered by Valyu semantic search.
FreedomIntelligence / bio-blast-searchesRun BLAST searches against NCBI databases using Biopython's Bio.Blast module.
FreedomIntelligence / bio-clinical-databases-clinvar-lookupQuery ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF
FreedomIntelligence / bio-clinical-databases-gnomad-frequenciesQuery gnomAD for population allele frequencies to assess variant rarity
FreedomIntelligence / bio-clinical-databases-hla-typingCall HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications
FreedomIntelligence / bio-clinical-databases-myvariant-queriesQuery myvariant.info API for aggregated variant annotations from multiple databases (ClinVar, gnomAD, dbSNP, COSMIC, etc.) in a single request
FreedomIntelligence / bio-clinical-databases-pharmacogenomicsQuery PharmGKB and CPIC for drug-gene interactions, pharmacogenomic annotations, and dosing guidelines
FreedomIntelligence / bio-clinical-databases-polygenic-riskCalculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics
FreedomIntelligence / bio-clinical-databases-tumor-mutational-burdenCalculate tumor mutational burden from panel or WES data with proper normalization and clinical thresholds
FreedomIntelligence / bio-clinical-databases-variant-prioritizationFilter and prioritize variants by pathogenicity, population frequency, and clinical evidence for rare disease analysis
FreedomIntelligence / bio-entrez-fetchRetrieve records from NCBI databases using Biopython's Entrez module (EFetch, ESummary utilities).
