12,194 skills found · Page 374 of 407
jaechang-hits / sar-analysisStructure-activity relationship (SAR) analysis guide for drug discovery including molecular descriptor analysis, scaffold analysis, and activity cliff detection.
jaechang-hits / depmap-crispr-essentialityDepMap CRISPR gene effect (Chronos) analysis: sign convention for essentiality, per-gene NaN-safe Spearman correlation, data loading/alignment. For general NaN-safe correlation see nan-safe-correlation; for quality filtering see degenerate-input-filtering.
jaechang-hits / general-figure-guideUniversal QA checklist for generated scientific plots: overlapping labels, clipped text, missing axes/legends, overcrowded data, and cross-journal resolution/format guidance.
jaechang-hits / hypothesis-generationStructured hypothesis formulation: turn observations into testable hypotheses with predictions, propose mechanisms, design experiments. Follows the scientific method. Use scientific-brainstorming for open ideation; hypogenic for automated LLM hypothesis testing on datasets.
jaechang-hits / peer-review-methodologyStructured peer review of manuscripts and grants. 7-stage evaluation: initial assessment, section review, statistical rigor, reproducibility, figure integrity, ethics, writing. Covers CONSORT/STROBE/PRISMA and report structure.
giuseppe-trisciuoglio / drawio-logical-diagramsCreates professional logical flow diagrams and logical system architecture diagrams using draw.io XML format (.drawio files)
giuseppe-trisciuoglio / aws-sdk-java-v2-bedrockProvides Amazon Bedrock patterns using AWS SDK for Java 2.x. Invokes foundation models (Claude, Llama, Titan), generates text and images, creates embeddings for RAG, streams real-time responses, and configures Spring Boot integration
giuseppe-trisciuoglio / clean-architectureProvides implementation patterns for Clean Architecture, Hexagonal Architecture (Ports & Adapters), and Domain-Driven Design in Java 21+ Spring Boot 3.5+ applications
giuseppe-trisciuoglio / langchain4j-rag-implementation-patternsProvides Retrieval-Augmented Generation (RAG) implementation patterns with LangChain4j for Java. Generates document ingestion pipelines, embedding stores, vector search, and semantic search capabilities
giuseppe-trisciuoglio / spring-boot-project-creatorCreates and scaffolds a new Spring Boot project (3.x or 4.x) by downloading from Spring Initializr, generating package structure (DDD or Layered architecture), configuring JPA, SpringDoc OpenAPI, and Docker Compose services (PostgreSQL, Redis, MongoDB)
giuseppe-trisciuoglio / spring-boot-security-jwtProvides JWT authentication and authorization patterns for Spring Boot 3.5.x covering token generation with JJWT, Bearer/cookie authentication, database/OAuth2 integration, and RBAC/permission-based access control using Spring Security 6.x
giuseppe-trisciuoglio / codexProvides Codex CLI delegation workflows for complex code generation and development tasks using OpenAI's GPT-5.3-codex models, including English prompt formulation, execution flags, sandbox modes, and safe result handling
giuseppe-trisciuoglio / sonarqube-mcpProvides SonarQube and SonarCloud integration patterns via the Model Context Protocol (MCP) server. Enables quality gate monitoring, issue discovery and triaging, pre-push code analysis, and rule education directly in the agent workflow
giuseppe-trisciuoglio / nextjs-performanceExpert Next.js performance optimization skill covering Core Web Vitals, image/font optimization, caching strategies, streaming, bundle optimization, and Server Components best practices
giuseppe-trisciuoglio / aws-cloudformation-bedrockProvides AWS CloudFormation patterns for Amazon Bedrock resources including agents, knowledge bases, data sources, guardrails, prompts, flows, and inference profiles
giuseppe-trisciuoglio / aws-cloudformation-cloudfrontProvides AWS CloudFormation patterns for CloudFront distributions, origins (ALB, S3, Lambda@Edge, VPC Origins), CacheBehaviors, Functions, SecurityHeaders, parameters, Outputs and cross-stack references
giuseppe-trisciuoglio / aws-cloudformation-ecsProvides AWS CloudFormation patterns for ECS clusters, task definitions, services, container definitions, auto scaling, blue/green deployments, CodeDeploy integration, ALB integration, service discovery, monitoring, logging, template structure, parameters, outputs, and cross-stack references
giuseppe-trisciuoglio / aws-cloudformation-lambdaProvides AWS CloudFormation patterns for Lambda functions, layers, API Gateway integration, event sources, cold start optimization, monitoring, logging, template validation, and deployment workflows
giuseppe-trisciuoglio / aws-cost-optimizationProvides structured AWS cost optimization guidance using five pillars (right-sizing, elasticity, pricing models, storage optimization, monitoring) and twelve actionable best practices with executable AWS CLI examples
giuseppe-trisciuoglio / aws-drawio-architecture-diagramsCreates professional AWS architecture diagrams in draw.io XML format (.drawio files) using official AWS Architecture Icons (aws4 library)
giuseppe-trisciuoglio / chunking-strategyProvides chunking strategies for RAG systems. Generates chunk size recommendations (256-1024 tokens), overlap percentages (10-20%), and semantic boundary detection methods. Validates semantic coherence and evaluates retrieval precision/recall metrics
giuseppe-trisciuoglio / prompt-engineeringProvides workflows to write, debug, and optimize prompts for LLMs, including few-shot example selection, chain-of-thought structuring, system prompt design, and template composition
giuseppe-trisciuoglio / ragImplements document chunking, embedding generation, vector storage, and retrieval pipelines for Retrieval-Augmented Generation systems
giuseppe-trisciuoglio / docs-updaterProvides automated documentation updates by analyzing git changes between the current branch and the last release tag. Performs git diff analysis to identify modifications, then updates README.md, CHANGELOG.md following Keep a Changelog standard, and discovers documentation folders for contextual up…
giuseppe-trisciuoglio / learnProvides autonomous project pattern learning by analyzing the codebase to discover development conventions, architectural patterns, and coding standards, then generates project rule files in .claude/rules/
giuseppe-trisciuoglio / memory-md-managementProvides comprehensive memory file management capabilities including auditing, quality assessment, and targeted improvements for files such as CLAUDE.md
giuseppe-trisciuoglio / aws-rds-spring-boot-integrationProvides patterns to configure AWS RDS (Aurora, MySQL, PostgreSQL) with Spring Boot applications. Configures HikariCP connection pools, implements read/write splitting, sets up IAM database authentication, enables SSL connections, and integrates with AWS Secrets Manager
giuseppe-trisciuoglio / aws-sdk-java-v2-messagingProvides AWS messaging patterns using AWS SDK for Java 2.x for SQS queues and SNS topics. Handles sending/receiving messages, FIFO queues, DLQ, subscriptions, and pub/sub patterns
giuseppe-trisciuoglio / langchain4j-ai-services-patternsProvides patterns to build declarative AI Services with LangChain4j for LLM integration, chatbot development, AI agent implementation, and conversational AI in Java. Generates type-safe AI services using interface-based patterns, annotations, memory management, and tools integration
giuseppe-trisciuoglio / langchain4j-spring-boot-integrationProvides integration patterns for LangChain4j with Spring Boot. Configures AI model beans, sets up chat memory with Spring context, integrates RAG pipelines with Spring Data, and handles auto-configuration, dependency injection, and Spring ecosystem integration
